STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAM2Junctional adhesion molecule B. (298 aa)    
Predicted Functional Partners:
JAM3
Junctional adhesion molecule C.
    
0.991
ITGA4
Integrin alpha-4; Belongs to the integrin alpha chain family.
     
 0.968
TJP1-2
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.961
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
     
 0.948
F11R
Junctional adhesion molecule A.
    
0.928
PARD3
Partitioning defective 3-like protein isoform A.
    
 0.915
GORASP2
Golgi reassembly-stacking protein 2.
    
   0.590
GORASP1
Golgi reassembly-stacking protein 1.
    
   0.590
TJP1
Tight junction protein ZO-1 isoform A; Belongs to the MAGUK family.
    
 
 0.579
CLDN1
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.576
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.