STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNPLA4Patatin-like phospholipase domain-containing protein 4 isoform B. (407 aa)    
Predicted Functional Partners:
RDH12
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.918
RPE65
Retinoid isomerohydrolase.
     
 0.906
RDH10
Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.903
SDR16C5-1
Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.903
Y1Q_0003831
Epidermal retinol dehydrogenase 2-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.903
SDR16C5-2
Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.903
DHRS3
Short-chain dehydrogenase/reductase 3.
     
 0.903
CYP26A1
Cytochrome P450 26A1; Belongs to the cytochrome P450 family.
   
 
 0.901
RETSAT
All-trans-retinol 13,14-reductase.
     
 0.900
DHRS9
Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.900
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.