STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDE1Nuclear distribution nudE-like protein 1. (323 aa)    
Predicted Functional Partners:
DISC1-1
Disrupted in schizophrenia 1 protein isoform A.
    
 
 0.909
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 
 0.893
NUDC-1
Nuclear migration protein nudC isoform A.
     
 0.812
NDEL1
Nuclear distribution protein nudE-like 1.
  
 
 
0.748
TBC1D31
TBC1 domain family member 31.
    
 
 0.725
HAUS6
HAUS augmin-like complex subunit 6 isoform A.
     
 0.699
CDK1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.670
PLK1
Serine/threonine-protein kinase PLK.
     
 0.656
BUB3
Mitotic checkpoint protein BUB3.
     
 0.648
OFD1
Oral-facial-digital syndrome 1 protein isoform B.
    
 
 0.638
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.