STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP5Z1AP-5 complex subunit zeta-1 isoform B. (832 aa)    
Predicted Functional Partners:
AP5S1
AP-5 complex subunit sigma-1.
    
 0.746
AP4E1
AP-4 complex subunit epsilon-1 isoform A.
     
 0.584
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
     
 0.582
SPG21
Maspardin.
      
 0.539
ZFYVE26
Zinc finger FYVE domain-containing protein 26 isoform B.
      
 0.534
Y1Q_0000428
Uncharacterized protein.
      
 0.534
CUNH1orf27
Odr-4-like protein.
      
 0.463
AP2A2-2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
     
 0.451
AP5M1
AP-5 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
      
 0.447
SPG7
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
      
 0.446
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.