STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPPBNatriuretic peptides A. (140 aa)    
Predicted Functional Partners:
NPR3-1
Atrial natriuretic peptide receptor 3 isoform B.
    
 0.959
NPR2
Guanylate cyclase.
    
 0.957
IDE
Insulin-degrading enzyme isoform A; Belongs to the peptidase M16 family.
    
 
 0.757
CORIN
Atrial natriuretic peptide-converting enzyme isoform A.
     
 0.682
Y1Q_0006043
Uncharacterized protein.
      
 0.618
Y1Q_0009497
Uncharacterized protein.
    
 0.596
Y1Q_0006044
Receptor-type guanylate cyclase gcy-22-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.596
NPR2-2
Atrial natriuretic peptide receptor 2.
    
 0.596
NPR1
Guanylate cyclase.
    
 0.596
Y1Q_0009584
Guanylate cyclase.
    
 0.596
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.