Y1Q_0015726 protein (Alligator mississippiensis)

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Score

Y1Q_0015726

Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa)

Predicted Functional Partners:

HSD3B2

0.916

CYP7A1

0.912

STS

0.910

CYP21A2

0.906

CYP17A1

0.906

CYP11A1

0.904

CYP7B1

0.903

DHCR7

0.805

DHCR24

0.800

Y1Q_0016603

0.800

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP11A1	CYP17A1	A0A151MAJ0	A0A151NV24	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	0.945
CYP11A1	CYP21A2	A0A151MAJ0	A0A151M676	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family.	0.942
CYP11A1	CYP7A1	A0A151MAJ0	A0A151MNT9	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.509
CYP11A1	CYP7B1	A0A151MAJ0	A0A151MNN1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family.	0.948
CYP11A1	DHCR24	A0A151MAJ0	A0A151M4G4	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Delta(24)-sterol reductase.	0.832
CYP11A1	DHCR7	A0A151MAJ0	A0A151MBL2	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	7-dehydrocholesterol reductase isoform A.	0.856
CYP11A1	HSD3B2	A0A151MAJ0	A0A151M1V0	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	3 beta-hydroxysteroid dehydrogenase 1.	0.966
CYP11A1	STS	A0A151MAJ0	A0A151NW27	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Steryl-sulfatase.	0.900
CYP11A1	Y1Q_0015726	A0A151MAJ0	A0A151NKZ4	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.904
CYP11A1	Y1Q_0016603	A0A151MAJ0	A0A151MWC5	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	O-acyltransferase.	0.806
CYP17A1	CYP11A1	A0A151NV24	A0A151MAJ0	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.945
CYP17A1	CYP21A2	A0A151NV24	A0A151M676	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family.	0.913
CYP17A1	CYP7A1	A0A151NV24	A0A151MNT9	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.923
CYP17A1	CYP7B1	A0A151NV24	A0A151MNN1	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	25-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family.	0.916
CYP17A1	HSD3B2	A0A151NV24	A0A151M1V0	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	3 beta-hydroxysteroid dehydrogenase 1.	0.969
CYP17A1	STS	A0A151NV24	A0A151NW27	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	Steryl-sulfatase.	0.903
CYP17A1	Y1Q_0015726	A0A151NV24	A0A151NKZ4	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.906
CYP21A2	CYP11A1	A0A151M676	A0A151MAJ0	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.942
CYP21A2	CYP17A1	A0A151M676	A0A151NV24	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family.	Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.	0.913
CYP21A2	CYP7A1	A0A151M676	A0A151MNT9	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.544