STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Y1Q_0012981Uncharacterized protein. (135 aa)    
Predicted Functional Partners:
SQLE
Squalene monooxygenase.
  
 
 0.991
FDPS
Farnesyl pyrophosphate synthase isoform B; Belongs to the FPP/GGPP synthase family.
  
 0.932
GGPS1
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.928
PDSS2
Decaprenyl-diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.
  
 0.914
PDSS1
Decaprenyl-diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.
  
 0.914
FDFT1
Squalene synthase.
  
  
 
0.902
CYP51A1
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
  
 
 0.893
SC5D-1
Lathosterol oxidase isoform B; Belongs to the sterol desaturase family.
  
 
 0.880
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.877
NUS1
Dehydrodolichyl diphosphate syntase complex subunit NUS1.
   
 
 0.838
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.