STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNKCyclin-K; Belongs to the cyclin family. (585 aa)    
Predicted Functional Partners:
CDK13
Protein kinase domain-containing protein.
   
 0.958
CDK12
Cyclin-dependent kinase 12 isoform A.
   
 0.958
CDK9
Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily.
   
 0.952
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.937
SUPT5H
Transcription elongation factor SPT5 isoform A.
    
 0.905
CCNH
Cyclin-H; Belongs to the cyclin family.
     
 0.885
SUPT4H1
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.853
CCNC
Cyclin-C; Belongs to the cyclin family.
     
0.831
CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
   
 
 0.828
CNOT2
CCR4-NOT transcription complex subunit 2 isoform A.
   
 
 0.806
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.