STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL14N6-adenosine-methyltransferase subunit METTL14; Belongs to the MT-A70-like family. (428 aa)    
Predicted Functional Partners:
WTAP
Pre-mRNA-splicing regulator WTAP.
   
 0.992
METTL3
N6-adenosine-methyltransferase subunit; Belongs to the MT-A70-like family.
  
 
0.962
Y1Q_0000158
Uncharacterized protein.
    
 0.957
YTHDF3
YTH domain-containing family protein 3.
  
   
 0.908
ALKBH5
RNA demethylase ALKBH5.
   
  
 0.900
RBM15B
Putative RNA-binding protein 15B.
    
 
 0.882
YTHDC2
Putative ATP-dependent RNA helicase YTHDC2.
   
 
 0.873
YTHDC1
YTH domain-containing protein 1 isoform A.
   
 
 0.869
METTL16
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]
   
  
 0.856
RBM15
Putative RNA-binding protein 15.
    
 
 0.856
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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