STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXO6Forkhead box protein O6. (424 aa)    
Predicted Functional Partners:
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.969
AKT3-2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.969
AKT2
Non-specific serine/threonine protein kinase.
    
 0.969
USP7
Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family.
   
 0.964
FOXO4
Forkhead box protein O4.
  
 
0.942
STK11
Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily.
    
 0.932
SGK1
Serine/threonine-protein kinase Sgk1 isoform A; Belongs to the protein kinase superfamily.
    
 0.931
SGK2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.931
IKBKB-2
Uncharacterized protein.
    
 0.925
IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta.
    
 0.925
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.