dcd_3 protein (Streptomyces turgidiscabies) - STRING interaction network

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Score

dcd_3

Deoxycytidine triphosphate deaminase. (358 aa)

Predicted Functional Partners:

thyA2

0.589

ndkA

0.582

thyX

0.574

dut

0.573

pyrG

0.567

mazG

0.536

tdk

0.523

strL

0.475

rfbD

0.475

tmk

0.470

Your Current Organism:

Streptomyces turgidiscabies

NCBI taxonomy Id: 85558
Other names: ATCC 700248, CIP 105577, IFO 16080, JCM 10429, NBRC 16080, NRRL B-24078, S. turgidiscabies, strain SY9113

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dcd_3	dut	T45_00974	T45_05454	Deoxycytidine triphosphate deaminase.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.573
dcd_3	mazG	T45_00974	T45_02504	Deoxycytidine triphosphate deaminase.	Nucleoside triphosphate pyrophosphohydrolase.	0.536
dcd_3	ndkA	T45_00974	T45_00600	Deoxycytidine triphosphate deaminase.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.582
dcd_3	pyrG	T45_00974	T45_03585	Deoxycytidine triphosphate deaminase.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.567
dcd_3	rfbD	T45_00974	T45_06323	Deoxycytidine triphosphate deaminase.	DTDP-4-dehydrorhamnose reductase.	0.475
dcd_3	strL	T45_00974	T45_03778	Deoxycytidine triphosphate deaminase.	DTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.	0.475
dcd_3	tdk	T45_00974	T45_05438	Deoxycytidine triphosphate deaminase.	Thymidine kinase.	0.523
dcd_3	thyA2	T45_00974	T45_00969	Deoxycytidine triphosphate deaminase.	Thymidylate synthase 2.	0.589
dcd_3	thyX	T45_00974	T45_08112	Deoxycytidine triphosphate deaminase.	Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.	0.574
dcd_3	tmk	T45_00974	T45_00750	Deoxycytidine triphosphate deaminase.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.470
dut	dcd_3	T45_05454	T45_00974	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Deoxycytidine triphosphate deaminase.	0.573
dut	mazG	T45_05454	T45_02504	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Nucleoside triphosphate pyrophosphohydrolase.	0.595
dut	ndkA	T45_05454	T45_00600	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.974
dut	pyrG	T45_05454	T45_03585	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.454
dut	tdk	T45_05454	T45_05438	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Thymidine kinase.	0.990
dut	thyA2	T45_05454	T45_00969	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Thymidylate synthase 2.	0.990
dut	thyX	T45_05454	T45_08112	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.	0.981
dut	tmk	T45_05454	T45_00750	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.	0.933
mazG	dcd_3	T45_02504	T45_00974	Nucleoside triphosphate pyrophosphohydrolase.	Deoxycytidine triphosphate deaminase.	0.536
mazG	dut	T45_02504	T45_05454	Nucleoside triphosphate pyrophosphohydrolase.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.	0.595