node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACK53325.1 | ACK53379.1 | Tmz1t_0552 | Tmz1t_0606 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.908 |
ACK53325.1 | ACK53400.1 | Tmz1t_0552 | Tmz1t_0627 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | 0.908 |
ACK53325.1 | ACK53567.1 | Tmz1t_0552 | Tmz1t_0798 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: eba:ebA2619 sulfite reductase. | 0.957 |
ACK53325.1 | ACK54205.1 | Tmz1t_0552 | Tmz1t_1446 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rce:RC1_0523 Cys. | 0.978 |
ACK53325.1 | ACK54657.1 | Tmz1t_0552 | Tmz1t_1906 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azo:azo2193 O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.871 |
ACK53325.1 | ACR02286.1 | Tmz1t_0552 | Tmz1t_3693 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PFAM: aminotransferase class I and II; KEGG: azo:azo3380 putative transaminase. | 0.922 |
ACK53325.1 | ahcY | Tmz1t_0552 | Tmz1t_3842 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.861 |
ACK53325.1 | metZ | Tmz1t_0552 | Tmz1t_3055 | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.976 |
ACK53379.1 | ACK53325.1 | Tmz1t_0606 | Tmz1t_0552 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.908 |
ACK53379.1 | ACK53567.1 | Tmz1t_0606 | Tmz1t_0798 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: eba:ebA2619 sulfite reductase. | 0.640 |
ACK53379.1 | ACK54205.1 | Tmz1t_0606 | Tmz1t_1446 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rce:RC1_0523 Cys. | 0.983 |
ACK53379.1 | ACK54657.1 | Tmz1t_0606 | Tmz1t_1906 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: azo:azo2193 O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.965 |
ACK53379.1 | ACR02286.1 | Tmz1t_0606 | Tmz1t_3693 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: aminotransferase class I and II; KEGG: azo:azo3380 putative transaminase. | 0.934 |
ACK53379.1 | ahcY | Tmz1t_0606 | Tmz1t_3842 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.965 |
ACK53379.1 | ilvE | Tmz1t_0606 | Tmz1t_1209 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.534 |
ACK53379.1 | metXS | Tmz1t_0606 | Tmz1t_4066 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.820 |
ACK53379.1 | metZ | Tmz1t_0606 | Tmz1t_3055 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.983 |
ACK53400.1 | ACK53325.1 | Tmz1t_0627 | Tmz1t_0552 | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: eba:ebA4678 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.908 |
ACK53400.1 | ACK53567.1 | Tmz1t_0627 | Tmz1t_0798 | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: eba:ebA2619 sulfite reductase. | 0.924 |
ACK53400.1 | ACK54205.1 | Tmz1t_0627 | Tmz1t_1446 | PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dar:Daro_3137 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit. | Cystathionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rce:RC1_0523 Cys. | 0.909 |