STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1E3PM39P-loop containing nucleoside triphosphate hydrolase protein. (201 aa)    
Predicted Functional Partners:
A0A1E3PHR5
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.914
A0A1E3PS58
Mating-type switching protein swi10.
    
 0.895
A0A1E3PL14
RMI1_N domain-containing protein.
    
 0.894
A0A1E3PPJ4
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
 0.880
A0A1E3PHA8
Nuclear protein localization protein 4.
    
 0.875
A0A1E3PIX6
P-loop containing nucleoside triphosphate hydrolase protein.
    
 
 0.869
A0A1E3PEM4
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.853
A0A1E3PG93
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.853
A0A1E3PF61
ERCC4 domain-containing protein.
    
 0.848
A0A1E3PKU4
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.837
Your Current Organism:
Nadsonia fulvescens
NCBI taxonomy Id: 857566
Other names: N. fulvescens var. elongata DSM 6958, Nadsonia fulvescens var. elongata DSM 6958
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