STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtrAResponse regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (224 aa)    
Predicted Functional Partners:
mtrB
Two-component system sensor kinase; Signal transduction histidine kinase.
 0.999
CVAR_2748
Two-component system sensor kinase; Signal transduction histidine kinase.
 
 0.923
phoS
Two-component system sensor kinase; Signal transduction histidine kinase.
 
 0.879
CVAR_0712
Two-component system sensor kinase; Signal transduction histidine kinase.
 
 0.859
lpqB
Putative secreted protein.
     
 0.777
tmk
Thymidilate synthase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.730
sahH
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.723
CVAR_2175
Hypothetical protein.
       0.592
CVAR_2169
Hypothetical protein; Predicted amidophosphoribosyltransferases.
  
    0.553
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
  
 0.543
Your Current Organism:
Corynebacterium variabile
NCBI taxonomy Id: 858619
Other names: C. variabile DSM 44702, Corynebacterium variabile CIP 107183, Corynebacterium variabile DSM 44702, Corynebacterium variabile LMG S-19265, Corynebacterium variabile str. DSM 44702, Corynebacterium variabile strain DSM 44702
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.