STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgdAConserved hypothetical protein; Catalyzes the N-deacetylation of peptidoglycan (PG), an important mechanism that appears to confer lysozyme resistance and to mitigate host immune detection; this likely contributes to pathogen persistence in the host. The exact nature of the residue in PG that is deacetylated has not been determined. Is also able to catalyze the deacetylation of acetylated xylan, and, to a lesser extent, that of chitin and chitosan. Therefore, this enzyme might play a role during infection, considering that xylan-containing carbohydrate structures are among those common [...] (293 aa)    
Predicted Functional Partners:
HP_0309
Conserved hypothetical protein; Similar to PID:929801 SP:P55176 percent identity: 31.27; identified by sequence similarity; putative.
  
    0.761
HP_0312
Conserved hypothetical ATP-binding protein; Similar to GP:953179 percent identity: 34.05; identified by sequence similarity; putative.
 
     0.719
ansA
L-asparaginase II (ansB); Similar to PID:758652 PID:895919 SP:P50286 percent identity: 54.13; identified by sequence similarity; putative; Belongs to the asparaginase 1 family.
      0.699
HP_0311
Predicted coding region HP0311; Hypothetical protein; identified by GeneMark; putative.
  
    0.662
msrAB
Peptide methionine sulfoxide reductase (msrA); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.535
HP_0308
Predicted coding region HP0308; Hypothetical protein; identified by GeneMark; putative.
       0.531
hemL
Glutamate-1-semialdehyde 2,1-aminomutase (hemL); Similar to GB:D26562 SP:P23893 GB:X53696 PID:41621 PID:473813 percent identity: 51.30; identified by sequence similarity; putative.
       0.517
HP_0307
Predicted coding region HP0307; Hypothetical protein; identified by GeneMark; putative.
  
    0.506
HP_0305
Predicted coding region HP0305; Hypothetical protein; identified by GeneMark; putative.
       0.498
pyrC
Dihydroorotase (pyrC); Non-functional DHOase.
  
 
  0.437
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
Server load: low (28%) [HD]