STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliW1Predicted coding region HP1154; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (135 aa)    
Predicted Functional Partners:
csrA
Carbon storage regulator (csrA); A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
  
 
 0.983
flaA
Flagellin A (flaA); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.
  
 
 0.854
murG
Transferase, peptidoglycan synthesis (murG); Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
    0.823
HP_1030
fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative.
  
  
 0.800
HP_0751
Polar flagellin (flaG); Similar to GB:U12816 PID:551514 percent identity: 21.90; identified by sequence similarity; putative.
  
    0.780
HP_0295
Flagellin B homolog (fla); Similar to GB:L08907 SP:Q07911 PID:305389 GB:AE000511 PID:2313197 percent identity: 32.90; identified by sequence similarity; putative.
  
 
 0.771
flaB
Flagellin B (flaB); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.
  
 
 0.768
HP_1558
Flagellar basal-body rod protein (flgC); Proximal rod protein; similar to PID:1165277 PID:1196316 SP:Q57466 GB:AE000783 percent identity: 46.04; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
  
 
 0.675
valS
valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.667
HP_1031
Flagellar motor switch protein (fliM); Similar to PID:1165263 PID:1185056 GB:AE000783 percent identity: 34.41; identified by sequence similarity; putative.
  
  
 0.586
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.