STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HP_0285Conserved hypothetical protein; Similar to SP:P54462 PID:1303812 PID:1890061 GB:AL009126 percent identity: 30.84; identified by sequence similarity; putative. (418 aa)    
Predicted Functional Partners:
HP_0282
Predicted coding region HP0282; Hypothetical protein; identified by GeneMark; putative.
       0.837
aroB
3-dehydroquinate synthase (aroB); Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
       0.837
HP_0284
Conserved hypothetical integral membrane protein; Similar to GB:L77117 SP:Q58111 PID:1591415 percent identity: 29.18; identified by sequence similarity; putative.
       0.837
HP_0286
Cell division protein (ftsH); Similar to GB:D26185 SP:P37476 PID:467458 GB:AL009126 percent identity: 41.16; identified by sequence similarity; putative; Belongs to the AAA ATPase family.
     
 0.837
HP_0287
Predicted coding region HP0287; Hypothetical protein; identified by GeneMark; putative.
       0.837
HP_0288
Predicted coding region HP0288; Hypothetical protein; identified by GeneMark; putative.
       0.747
tgt
tRNA-guanine transglycosylase (tgt); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to for [...]
  
  
 0.637
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
  
 0.628
HP_0289
Toxin-like outer membrane protein; Similar to SP:Q48245 PID:2228502 PID:2327044 PID:2327046 PID:471729 percent identity: 30.59; identified by sequence similarity; putative.
       0.559
HP_0293
Para-aminobenzoate synthetase (pabB); Similar to GB:K02673 SP:P05041 GB:U07748 GB:U07749 GB:U07755 percent identity: 35.09; identified by sequence similarity; putative.
  
    0.483
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.