STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmhBConserved hypothetical protein; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position; Belongs to the GmhB family. (173 aa)    
Predicted Functional Partners:
gmhA
Phosphoheptose isomerase (gmhA); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
 
 0.999
hldE
ADP-heptose synthase (rfaE); Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
  
 0.998
HP_1191
ADP-heptose-lps heptosyltransferase II (rfaF); Similar to GB:L42023 SP:P45042 PID:1006405 PID:1221223 PID:1205353 percent identity: 33.22; identified by sequence similarity; putative.
 
 0.950
HP_0859
ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD); Similar to SP:P37420 GB:U06472 GB:X52093 PID:459160 percent identity: 32.73; identified by sequence similarity; putative.
  
 
 0.933
HP_0360
UDP-glucose 4-epimerase; Similar to GB:Z25478 PID:396521 SP:Q59083 percent identity: 43.08; identified by sequence similarity; putative; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
    
 0.907
HP_0861
Predicted coding region HP0861; Hypothetical protein; identified by GeneMark; putative.
  
    0.838
coaX
Predicted coding region HP0862; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. Can also utilize CTP or GTP instead of ATP as a phosphoryl donor, albeit to a lesser extent.
  
    0.837
pgbB
Predicted coding region HP0863; Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.pylori to degrade host components.
       0.837
HP_0864
Predicted coding region HP0864; Hypothetical protein; identified by GeneMark; putative.
       0.837
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.837
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.