STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HP_1032Alternative transcription initiation factor, sigma-F (fliA); Similar to SP:P31804 GB:L36677 GB:U18539 PID:556180 PID:687650 percent identity: 35.07; identified by sequence similarity; putative. (255 aa)    
Predicted Functional Partners:
HP_1031
Flagellar motor switch protein (fliM); Similar to PID:1165263 PID:1185056 GB:AE000783 percent identity: 34.41; identified by sequence similarity; putative.
 
 
 0.994
HP_1030
fliY protein (fliY); Similar to GB:M86738 SP:P24073 PID:142926 PID:551704 GB:AL009126 percent identity: 29.27; identified by sequence similarity; putative.
 
  
 0.992
rpoBC
DNA-directed RNA polymerase, beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.976
HP_1559
Flagellar basal-body rod protein (flgB); Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
 
 0.976
HP_1119
Flagellar hook-associated protein 1 (HAP1) (flgK); Similar to GB:X51738 SP:P15932 GB:X52093 PID:47679 percent identity: 27.56; identified by sequence similarity; putative.
 
  
 0.971
HP_1558
Flagellar basal-body rod protein (flgC); Proximal rod protein; similar to PID:1165277 PID:1196316 SP:Q57466 GB:AE000783 percent identity: 46.04; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
 
 
 0.961
fliD
Flagellar hook-associated protein 2 (fliD); Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription.
 
  
 0.937
rpoA
DNA-directed RNA polymerase, alpha subunit (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.935
fliG
Flagellar motor switch protein (fliG); One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation. Required for flagellum synthesis and motility. In H.pylori four flagellar switch proteins are encoded, FliG, FliM, FliN and FliY.
 
  
 0.928
HP_0809
Predicted coding region HP0809; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
  
 0.923
Your Current Organism:
Helicobacter pylori
NCBI taxonomy Id: 85962
Other names: H. pylori 26695, Helicobacter pylori (strain 26695), Helicobacter pylori 26695, Helicobacter pylori ATCC 700392, Helicobacter pylori KE26695, Helicobacter pylori str. 26695, Helicobacter pylori strain 26695
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.