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ilvE protein (Helicobacter pylori J99) - STRING interaction network
"ilvE" - Branched-chain-amino-acid aminotransferase in Helicobacter pylori J99
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
ilvEBranched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family (340 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family (270 aa)
       
  0.914
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily (293 aa)
   
 
  0.830
hom
Homoserine dehydrogenase; Similar to H. pylori 26695 gene HP0822 (421 aa)
   
 
  0.819
porB
Pyruvate ferrodoxin oxidoreductase; Similar to H. pylori 26695 gene HP1111 (314 aa)
         
    0.800
porA
Pyruvate ferrodoxin oxidoreductase; Similar to H. pylori 26695 gene HP1110 (407 aa)
         
    0.800
porD
Pyruvate ferrodoxin oxidoreductase; Similar to H. pylori 26695 gene HP1109 (130 aa)
         
    0.800
porG
Pyruvate ferrodoxin oxidoreductase; Similar to H. pylori 26695 gene HP1108 (186 aa)
         
    0.800
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate; Belongs to the ketol-acid reductoisomerase family (330 aa)
   
 
  0.752
jhp_1362
Putative Outer membrane protein; Similar to H. pylori 26695 gene HP1469 (248 aa)
              0.682
putA
Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family (1185 aa)
   
 
  0.653
Your Current Organism:
Helicobacter pylori J99
NCBI taxonomy Id: 85963
Other names: H. pylori J99, Helicobacter pylori J99, Helicobacter pylori str. J99, Helicobacter pylori strain J99
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