STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Experiments
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[Homology]
Score
AEK23212.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (853 aa)    
Predicted Functional Partners:
eno
2-phospho-D-glycerate hydro-lyase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.929
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 
 0.928
AEK22395.1
Short=PK; Pyruvate kinase, alpha/beta (PF02887); Pyruvate/Phosphoenolpyruvate kinase, catalytic core (G3DSA:3.20.20.60); Pyruvate kinase (TIGR01064); Pyruvate kinase, beta-barrel-like (SSF50800); Pyruvate kinase, barrel (PR01050); Pyruvate/Phosphoenolpyruvate kinase, catalytic core (SSF51621); Pyruvate kinase, barrel (PF00224); Pyruvate kinase (PTHR11817); Pyruvate kinase, C-terminal-like (SSF52935); Pyruvate kinase, active site (PS00110); Pyruvate kinase, alpha/beta (G3DSA:3.40.1380.20); Protein involved in catalytic activity, magnesium ion binding, pyruvate kinase activity, potassium [...]
     
 0.927
pckA
Phosphoenolpyruvate carboxylase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.927
AEK23466.1
Citrate synthase-like, core (SSF48256); Citrate synthase-like (PR00143); Citrate synthase, type II (TIGR01798); Citrate synthase active site (PS00480); Citrate synthase-like, large alpha subdomain (G3DSA:1.10.580.10); Citrate synthase-like (PTHR11739); Citrate synthase-like (PF00285); Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer, citrate (Si)-synthase activity, cellular carbohydrate metabolic process and tricarboxylic acid cycle.
     
 0.855
AEK24070.1
Putative homoserine O-acetyltransferase; Weak similarity to UniProt:Q73UB0.
 
  
 0.597
AEK24069.1
N-terminus: TMH(LipoP); AltName: Full=Homoserine O-trans-acetylase;Short=Homoserine transacetylase;Short=HTA; 1 transmembrane domain; Alpha/beta hydrolase fold-1 (PF00561); alpha/beta-Hydrolases (SSF53474).
 
  
 0.548
AEK23213.1
Regulatory protein asnC; Dimeric alpha-beta barrel (SSF54909); Transcription regulator AsnC-type, C-terminal (PF01037); Undefined Gene3D domain (G3DSA:3.30.70.920); Transcription regulator AsnC-type (SM00344); HTH transcriptional regulator, AsnC-type (PS50956); Winged helix DNA-binding domain (SSF46785); Winged helix-turn-helix transcription repressor DNA-binding (G3DSA:1.10.10.10); HTH transcriptional regulator, AsnC-type (PR00033); Protein involved in transcription factor activity, sequence-specific DNA binding and regulation of transcription, DNA-dependent.
       0.546
AEK24068.1
AltName: Full=Aspartokinase I/homoserine dehydrogenase I;Short=AKI-HDI;Includes:RecName: Full=Aspartokinase;Includes:RecName: Full=Homoserine dehydrogenase; Aspartate/glutamate/uridylate kinase (SSF53633); NAD(P)-binding domain (G3DSA:3.40.50.720); Homoserine dehydrogenase, conserved site (PS01042); Amino acid-binding ACT (PF01842); Homoserine dehydrogenase, catalytic (PF00742); Aspartate/glutamate/uridylate kinase (G3DSA:3.40.1160.10); Bifunctional aspartokinase/homoserine dehydrogenase I (PIRSF000727); Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain (SSF55347); Aspar [...]
  
  
 0.481
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.470
Your Current Organism:
Capnocytophaga canimorsus
NCBI taxonomy Id: 860228
Other names: C. canimorsus Cc5, Capnocytophaga canimorsus Cc5, Capnocytophaga canimorsus str. Cc5, Capnocytophaga canimorsus strain Cc5
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