node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CLCR_08078 | NAT10 | A0A1C1CR81 | A0A1C1CEG4 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.626 |
CLCR_08078 | NOP14 | A0A1C1CR81 | A0A1C1CZY7 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | Putative nucleolar complex protein 14. | 0.495 |
CLCR_08078 | PUS1 | A0A1C1CR81 | A0A1C1CXS0 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | tRNA pseudouridine synthase 1. | 0.625 |
CLCR_08078 | TRM82 | A0A1C1CR81 | A0A1C1CI78 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.609 |
CLCR_08078 | dus3 | A0A1C1CR81 | A0A1C1CNV4 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. | 0.715 |
CLCR_08078 | erb1 | A0A1C1CR81 | A0A1C1CYT5 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.776 |
CLCR_08078 | spb1 | A0A1C1CR81 | A0A1C1CAB1 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. | 0.534 |
CLCR_08078 | trm61 | A0A1C1CR81 | A0A1C1D291 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | tRNA (Adenine(58)-N(1))-methyltransferase catalytic subunit trm61. | 0.564 |
CLCR_08078 | trm8 | A0A1C1CR81 | A0A1C1CD57 | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.753 |
NAT10 | CLCR_08078 | A0A1C1CEG4 | A0A1C1CR81 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.626 |
NAT10 | NOP14 | A0A1C1CEG4 | A0A1C1CZY7 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | Putative nucleolar complex protein 14. | 0.998 |
NAT10 | PUS1 | A0A1C1CEG4 | A0A1C1CXS0 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA pseudouridine synthase 1. | 0.501 |
NAT10 | TRM82 | A0A1C1CEG4 | A0A1C1CI78 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.602 |
NAT10 | dus3 | A0A1C1CEG4 | A0A1C1CNV4 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. | 0.708 |
NAT10 | erb1 | A0A1C1CEG4 | A0A1C1CYT5 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.889 |
NAT10 | spb1 | A0A1C1CEG4 | A0A1C1CAB1 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. | 0.898 |
NAT10 | trm61 | A0A1C1CEG4 | A0A1C1D291 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA (Adenine(58)-N(1))-methyltransferase catalytic subunit trm61. | 0.838 |
NAT10 | trm8 | A0A1C1CEG4 | A0A1C1CD57 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.708 |
NOP14 | CLCR_08078 | A0A1C1CZY7 | A0A1C1CR81 | Putative nucleolar complex protein 14. | N2,N2-dimethylguanosine tRNA methyltransferase family protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.495 |
NOP14 | NAT10 | A0A1C1CZY7 | A0A1C1CEG4 | Putative nucleolar complex protein 14. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.998 |