STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiEMethylase involved in ubiquinone/menaquinone biosynthesis; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (248 aa)    
Predicted Functional Partners:
AIF81082.1
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
  
 
 0.938
AIF80658.1
COG2941 Ubiquinone biosynthesis protein COQ7; Belongs to the COQ7 family.
  
 
 0.916
AIF80870.1
COG0655 Multimeric flavodoxin WrbA.
     
  0.900
AIF81884.1
NADPH-dependent FMN reductase; COG0655 Multimeric flavodoxin WrbA.
     
  0.900
ubiA
4-hydroxybenzoate polyprenyltransferase-like prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
   
 0.802
AIF81176.1
N-acetylmuramoyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression.
     
 0.774
ubiG
Bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 
 0.684
AIF81173.1
COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.
       0.521
AIF81174.1
Hypothetical protein; COG0767 ABC-type transport system involved in resistance to organic solvents, permease component.
       0.521
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.521
Your Current Organism:
endosymbiont of Acanthamoeba
NCBI taxonomy Id: 86106
Other names: e. of Acanthamoeba sp. UWC8, endosymbiont of Acanthamoeba sp. UWC8
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