node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alaS | guaA | AARI_17300 | AARI_22540 | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.644 |
alaS | ileS | AARI_17300 | AARI_18280 | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.703 |
alaS | leuS | AARI_17300 | AARI_16990 | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | leucine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.784 |
alaS | pheS | AARI_17300 | AARI_11300 | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | phenylalanine--tRNA ligase subunit alpha; Activates phenylalanine and transfers it to tRNA(Phe) as the first step in protein biosynthesis; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.465 |
alaS | pheT | AARI_17300 | AARI_11310 | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | phenylalanine--tRNA ligase subunit beta; Activates phenylalanine and transfers it to tRNA(Phe) as the first step in protein biosynthesis; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.965 |
alaS | rpsB | AARI_17300 | AARI_09640 | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.465 |
alaS | thrS | AARI_17300 | AARI_17620 | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | threonine--tRNA ligase; Activates threonine and transfers it to tRNA(Thr) as the first step in protein biosynthesis; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.745 |
guaA | alaS | AARI_22540 | AARI_17300 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.644 |
guaA | ileS | AARI_22540 | AARI_18280 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.728 |
guaA | leuS | AARI_22540 | AARI_16990 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | leucine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.597 |
guaA | pheS | AARI_22540 | AARI_11300 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | phenylalanine--tRNA ligase subunit alpha; Activates phenylalanine and transfers it to tRNA(Phe) as the first step in protein biosynthesis; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.585 |
guaA | pheT | AARI_22540 | AARI_11310 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | phenylalanine--tRNA ligase subunit beta; Activates phenylalanine and transfers it to tRNA(Phe) as the first step in protein biosynthesis; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.945 |
guaA | pyrD | AARI_22540 | AARI_16750 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.624 |
guaA | rpoB | AARI_22540 | AARI_23600 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.842 |
guaA | rpsB | AARI_22540 | AARI_09640 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.694 |
guaA | thrS | AARI_22540 | AARI_17620 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | threonine--tRNA ligase; Activates threonine and transfers it to tRNA(Thr) as the first step in protein biosynthesis; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.704 |
ileS | alaS | AARI_18280 | AARI_17300 | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | alanine-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.703 |
ileS | guaA | AARI_18280 | AARI_22540 | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.728 |
ileS | leuS | AARI_18280 | AARI_16990 | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | leucine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.971 |
ileS | pheS | AARI_18280 | AARI_11300 | isoleucine-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | phenylalanine--tRNA ligase subunit alpha; Activates phenylalanine and transfers it to tRNA(Phe) as the first step in protein biosynthesis; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.580 |