STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arsBArsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. (360 aa)    
Predicted Functional Partners:
arsC
ArsC reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.988
AARI_31980
Identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions.
  
  
 0.705
AARI_31950
Conserved hypothetical secreted protein; Signal peptide predicted by SignalP 3.0 HMM (probability: 0.502) with cleavage site probability 0.387 between position 20 and 21.
     
 0.677
AARI_27780
Low molecular weight protein-tyrosine-phosphatase; Identified by match to protein family PF01451. Protein tyrosine (pTyr) phosphorylation is a common post-translational modification which can create novel recognition motifs for protein interactions and cellular localisation, affect protein stability, and regulate enzyme activity. Consequently, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC:3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine residue, [...]
  
  
 0.525
AARI_16580
Putative sodium-dependent transporter; Identified by match to protein family PF01758. Bile acid:Na+ symporter (BASS) family (TC 2.A.28.y.z): these symporters exhibit broad specificity, taking up a variety of non bile organic compounds as well as taurocholate and other bile salts.
  
   
 0.451
lpdA-2
E3 component of pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes.
      
 0.434
pstB
Phosphate ABC transporter, ATP-binding subunit PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.401
Your Current Organism:
Glutamicibacter arilaitensis
NCBI taxonomy Id: 861360
Other names: Arthrobacter arilaitensis CIP 108037, Arthrobacter arilaitensis Re117, G. arilaitensis Re117, Glutamicibacter arilaitensis Re117
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