node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AARI_16580 | arsB | AARI_16580 | AARI_31970 | Putative sodium-dependent transporter; Identified by match to protein family PF01758. Bile acid:Na+ symporter (BASS) family (TC 2.A.28.y.z): these symporters exhibit broad specificity, taking up a variety of non bile organic compounds as well as taurocholate and other bile salts. | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | 0.451 |
AARI_27780 | arsB | AARI_27780 | AARI_31970 | Low molecular weight protein-tyrosine-phosphatase; Identified by match to protein family PF01451. Protein tyrosine (pTyr) phosphorylation is a common post-translational modification which can create novel recognition motifs for protein interactions and cellular localisation, affect protein stability, and regulate enzyme activity. Consequently, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC:3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine residue, [...] | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | 0.525 |
AARI_31950 | AARI_31980 | AARI_31950 | AARI_31980 | Conserved hypothetical secreted protein; Signal peptide predicted by SignalP 3.0 HMM (probability: 0.502) with cleavage site probability 0.387 between position 20 and 21. | Identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions. | 0.482 |
AARI_31950 | arsB | AARI_31950 | AARI_31970 | Conserved hypothetical secreted protein; Signal peptide predicted by SignalP 3.0 HMM (probability: 0.502) with cleavage site probability 0.387 between position 20 and 21. | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | 0.677 |
AARI_31950 | arsC | AARI_31950 | AARI_31960 | Conserved hypothetical secreted protein; Signal peptide predicted by SignalP 3.0 HMM (probability: 0.502) with cleavage site probability 0.387 between position 20 and 21. | ArsC reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.657 |
AARI_31980 | AARI_31950 | AARI_31980 | AARI_31950 | Identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions. | Conserved hypothetical secreted protein; Signal peptide predicted by SignalP 3.0 HMM (probability: 0.502) with cleavage site probability 0.387 between position 20 and 21. | 0.482 |
AARI_31980 | arsB | AARI_31980 | AARI_31970 | Identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions. | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | 0.705 |
AARI_31980 | arsC | AARI_31980 | AARI_31960 | Identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions. | ArsC reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.702 |
arsB | AARI_16580 | AARI_31970 | AARI_16580 | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | Putative sodium-dependent transporter; Identified by match to protein family PF01758. Bile acid:Na+ symporter (BASS) family (TC 2.A.28.y.z): these symporters exhibit broad specificity, taking up a variety of non bile organic compounds as well as taurocholate and other bile salts. | 0.451 |
arsB | AARI_27780 | AARI_31970 | AARI_27780 | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | Low molecular weight protein-tyrosine-phosphatase; Identified by match to protein family PF01451. Protein tyrosine (pTyr) phosphorylation is a common post-translational modification which can create novel recognition motifs for protein interactions and cellular localisation, affect protein stability, and regulate enzyme activity. Consequently, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC:3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine residue, [...] | 0.525 |
arsB | AARI_31950 | AARI_31970 | AARI_31950 | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | Conserved hypothetical secreted protein; Signal peptide predicted by SignalP 3.0 HMM (probability: 0.502) with cleavage site probability 0.387 between position 20 and 21. | 0.677 |
arsB | AARI_31980 | AARI_31970 | AARI_31980 | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | Identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions. | 0.705 |
arsB | arsC | AARI_31970 | AARI_31960 | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | ArsC reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.988 |
arsB | lpdA-2 | AARI_31970 | AARI_10940 | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | E3 component of pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes. | 0.434 |
arsB | pstB | AARI_31970 | AARI_01180 | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | Phosphate ABC transporter, ATP-binding subunit PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.401 |
arsC | AARI_31950 | AARI_31960 | AARI_31950 | ArsC reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Conserved hypothetical secreted protein; Signal peptide predicted by SignalP 3.0 HMM (probability: 0.502) with cleavage site probability 0.387 between position 20 and 21. | 0.657 |
arsC | AARI_31980 | AARI_31960 | AARI_31980 | ArsC reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Identified by match to PF01022: bacterial regulatory protein, ArsR family. ArsR-family transcriptional regulators include several proteins that appear to dissociate from DNA in the presence of metal ions. | 0.702 |
arsC | arsB | AARI_31960 | AARI_31970 | ArsC reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | 0.988 |
lpdA-2 | arsB | AARI_10940 | AARI_31970 | E3 component of pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes. | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | 0.434 |
pstB | arsB | AARI_01180 | AARI_31970 | Phosphate ABC transporter, ATP-binding subunit PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | Arsenical Resistance-3 (ACR3) Family, ArsB arsenite/antimonite exporter (TC 2.A.59.1.2). Identified by similarity to protein SP: P45946 (Bacillus subtilis). Confers resistance to arsenite by allowing cells to extrude this compound. | 0.401 |