node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEA00408.1 | AEA00635.1 | HMPREF9243_0580 | HMPREF9243_0733 | Identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; Belongs to the LOG family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.445 |
AEA00408.1 | AEA00911.1 | HMPREF9243_0580 | HMPREF9243_0415 | Identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; Belongs to the LOG family. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.445 |
AEA00408.1 | AEA01051.1 | HMPREF9243_0580 | HMPREF9243_0731 | Identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; Belongs to the LOG family. | Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268. | 0.501 |
AEA00635.1 | AEA00408.1 | HMPREF9243_0733 | HMPREF9243_0580 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; Belongs to the LOG family. | 0.445 |
AEA00635.1 | AEA00911.1 | HMPREF9243_0733 | HMPREF9243_0415 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.900 |
AEA00635.1 | AEA01051.1 | HMPREF9243_0733 | HMPREF9243_0731 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268. | 0.999 |
AEA00635.1 | AEA01714.1 | HMPREF9243_0733 | HMPREF9243_1006 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
AEA00635.1 | adk | HMPREF9243_0733 | HMPREF9243_0529 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.917 |
AEA00635.1 | cmk | HMPREF9243_0733 | HMPREF9243_1355 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.922 |
AEA00635.1 | nrdI | HMPREF9243_0733 | HMPREF9243_0732 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | nrdI protein; Probably involved in ribonucleotide reductase function. | 0.978 |
AEA00635.1 | pyk | HMPREF9243_0733 | HMPREF9243_1372 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.914 |
AEA00635.1 | tmk | HMPREF9243_0733 | HMPREF9243_0438 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.934 |
AEA00911.1 | AEA00408.1 | HMPREF9243_0415 | HMPREF9243_0580 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; Belongs to the LOG family. | 0.445 |
AEA00911.1 | AEA00635.1 | HMPREF9243_0415 | HMPREF9243_0733 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.900 |
AEA00911.1 | AEA01051.1 | HMPREF9243_0415 | HMPREF9243_0731 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Ribonucleoside-diphosphate reductase, beta subunit; Identified by match to protein family HMM PF00268. | 0.997 |
AEA00911.1 | AEA01714.1 | HMPREF9243_0415 | HMPREF9243_1006 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
AEA00911.1 | adk | HMPREF9243_0415 | HMPREF9243_0529 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.917 |
AEA00911.1 | cmk | HMPREF9243_0415 | HMPREF9243_1355 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.922 |
AEA00911.1 | nrdI | HMPREF9243_0415 | HMPREF9243_0732 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | nrdI protein; Probably involved in ribonucleotide reductase function. | 0.768 |
AEA00911.1 | pyk | HMPREF9243_0415 | HMPREF9243_1372 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.914 |