STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY74136.1Protein of unknown function UPF0254; COGs: COG4016 conserved hypothetical protein; InterPro IPR009625; KEGG: mvu:Metvu_0907 hypothetical protein; PFAM: Uncharacterised protein family UPF0254; SPTR: UPF0254 protein Metvu_0907; PFAM: Uncharacterised protein family (UPF0254). (171 aa)    
Predicted Functional Partners:
ADY74132.1
Roadblock/LC7 family protein; COGs: COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid; InterPro IPR004942; KEGG: rrs:RoseRS_3912 roadblock/LC7 family protein; PFAM: Dynein light chain-related; SPTR: Roadblock/LC7 family protein; PFAM: Roadblock/LC7 domain.
       0.773
ADY74133.1
Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR007197: IPR006638; KEGG: mmp:MMP0126 biotin synthase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthetase; PFAM: Radical SAM superfamily.
       0.773
ADY74134.1
Protein of unknown function DUF1188; COGs: COG4019 conserved hypothetical protein; InterPro IPR009573; KEGG: mvu:Metvu_0359 hypothetical protein; PFAM: Protein of unknown function DUF1188; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1188); Protein of unknown function (DUF3236).
       0.773
ADY74135.1
NGG1p interacting factor 3 protein, NIF3; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: mru:mru_0531 NIF3 family protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: NIF3 family protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family.
       0.773
ADY74137.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG4015 dinucleotide-utilizing protein of the ThiF/HesA family; InterPro IPR000594; KEGG: mmx:MmarC6_1430 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family.
       0.773
ADY74138.1
COGs: COG4018 conserved hypothetical protein; InterPro IPR016760; KEGG: mla:Mlab_1745 hypothetical protein; PFAM: Uncharacterised conserved protein UCP019375; SPTR: Uncharacterized protein-like protein; PFAM: Fibrillarin-like archaeal protein.
       0.773
ADY74131.1
Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein; COGs: COG4007 dehydrogenase related to H2-forming N5 N10-methylenetetrahydromethanopterin dehydrogenase; InterPro IPR010063: IPR004889; KEGG: mja:MJ_1338 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-like protein; PFAM: H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase; SPTR: H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338; TIGRFAM: Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related; PFAM: H2-fo [...]
       0.675
ADY74124.1
AAA ATPase; COGs: COG1484 DNA replication protein; InterPro IPR003593; KEGG: sul:SYO3AOP1_1254 DNA replication protein DnaC; SMART: ATPase, AAA+ type, core; SPTR: DNA replication protein DnaC; PFAM: IstB-like ATP binding protein.
       0.545
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.545
ADY74126.1
NHL repeat containing protein; InterPro IPR001258; KEGG: mlo:mll4586 periplasmic ATP/GTP-binding protein; PFAM: NHL repeat; SPTR: Periplasmic ATP/GTP-binding protein.
       0.545
Your Current Organism:
Desulfurobacterium thermolithotrophum
NCBI taxonomy Id: 868864
Other names: D. thermolithotrophum DSM 11699, Desulfurobacterium thermolithotrophum BSA, Desulfurobacterium thermolithotrophum DSM 11699, Desulfurobacterium thermolithotrophum str. DSM 11699, Desulfurobacterium thermolithotrophum strain DSM 11699
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