STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (195 aa)    
Predicted Functional Partners:
AFM11234.1
Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.995
AFM11844.1
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
  
 
 0.995
AFM12029.1
Xylene monooxygenase electron transfer component; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001041:IPR008333:IPR001433; KEGG: hdn:Hden_0734 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase FAD-binding region; Ferredoxin; SPTR: Oxidoreductase FAD/NAD(P)-binding domain protein.
  
  
 0.974
carB
PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481:IPR005479:IPR005480:IPR011607:IPR006275; KEGG: lic:LIC12883 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl [...]
 
 
 0.967
pyrB
PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR002082:IPR006132:IPR006131; KEGG: lbf:LBF_0992 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamo [...]
 
  
 0.963
carA
PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: naz:Aazo_2282 carbamoyl-phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl phosphate synthase, small subunit; Belongs to the CarA family.
 
  
 0.957
AFM11940.1
Allantoinase; PFAM: Amidohydrolase family; TIGRFAM: allantoinase; dihydroorotase, multifunctional complex type; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR017593:IPR006680; KEGG: hch:HCH_01096 dihydroorotase-like protein; PFAM: Amidohydrolase 1; SPTR: Dihydroorotase and related cyclic amidoHydrolase; TIGRFAM: Allantoinase.
  
  
 0.957
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
 
 0.881
AFM11287.1
Protein of unknown function DUF6 transmembrane; PFAM: EamA-like transporter family; InterPro IPR000620; KEGG: pol:Bpro_0672 hypothetical protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein.
       0.778
AFM11285.1
Hypothetical protein.
       0.773
Your Current Organism:
Turneriella parva
NCBI taxonomy Id: 869212
Other names: T. parva DSM 21527, Turneriella parva DSM 21527, Turneriella parva H, Turneriella parva NCTC 11395, Turneriella parva str. DSM 21527, Turneriella parva strain DSM 21527
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