STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpu_23000[FeFe] hydrogenase H-cluster maturation GTPase HydF. (405 aa)    
Predicted Functional Partners:
cpu_23010
[FeFe] hydrogenase H-cluster radical SAM maturase HydG.
   
 0.993
cpu_12850
[FeFe] hydrogenase H-cluster radical SAM maturase HydE.
   
 0.987
cpu_22990
Sigma-54-dependent Fis family transcriptional regulator.
     
 0.818
gpsA
Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.780
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
   
  
 0.752
cmk
Cytidylate kinase.
  
  
 0.685
cpu_04770
NADH dehydrogenase.
 
  
 0.665
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.642
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
   
 0.578
cpu_22830
16S rRNA pseudouridine(516) synthase; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.577
Your Current Organism:
Carboxydothermus pertinax
NCBI taxonomy Id: 870242
Other names: C. pertinax, Carboxydothermus pertinax Yoneda et al. 2012, Carboxydothermus sp. Ug1, DSM 23698, NBRC 107576, strain Ug1
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