node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A0C3KSB0 | A0A0C3NAG4 | A0A0C3KSB0 | A0A0C3NAG4 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein. | 0.972 |
A0A0C3KSB0 | A0A0C3NI95 | A0A0C3KSB0 | A0A0C3NI95 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Thymidylate_kin domain-containing protein. | 0.619 |
A0A0C3KSB0 | A0A0C3PNN1 | A0A0C3KSB0 | A0A0C3PNN1 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein. | 0.734 |
A0A0C3KSB0 | A0A0C3PSD7 | A0A0C3KSB0 | A0A0C3PSD7 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine amidotransferase type-1 domain-containing protein. | 0.793 |
A0A0C3KSB0 | A0A0C3PUF9 | A0A0C3KSB0 | A0A0C3PUF9 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Pribosyltran domain-containing protein. | 0.963 |
A0A0C3KSB0 | M404DRAFT_8727 | A0A0C3KSB0 | A0A0C3P106 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.980 |
A0A0C3NAG4 | A0A0C3KSB0 | A0A0C3NAG4 | A0A0C3KSB0 | Uncharacterized protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.972 |
A0A0C3NAG4 | A0A0C3NI95 | A0A0C3NAG4 | A0A0C3NI95 | Uncharacterized protein. | Thymidylate_kin domain-containing protein. | 0.520 |
A0A0C3NAG4 | A0A0C3PNN1 | A0A0C3NAG4 | A0A0C3PNN1 | Uncharacterized protein. | Uncharacterized protein. | 0.728 |
A0A0C3NAG4 | A0A0C3PSD7 | A0A0C3NAG4 | A0A0C3PSD7 | Uncharacterized protein. | Glutamine amidotransferase type-1 domain-containing protein. | 0.876 |
A0A0C3NAG4 | A0A0C3PUF9 | A0A0C3NAG4 | A0A0C3PUF9 | Uncharacterized protein. | Pribosyltran domain-containing protein. | 0.996 |
A0A0C3NAG4 | M404DRAFT_8727 | A0A0C3NAG4 | A0A0C3P106 | Uncharacterized protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.998 |
A0A0C3NI95 | A0A0C3KSB0 | A0A0C3NI95 | A0A0C3KSB0 | Thymidylate_kin domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.619 |
A0A0C3NI95 | A0A0C3NAG4 | A0A0C3NI95 | A0A0C3NAG4 | Thymidylate_kin domain-containing protein. | Uncharacterized protein. | 0.520 |
A0A0C3NI95 | A0A0C3PJ26 | A0A0C3NI95 | A0A0C3PJ26 | Thymidylate_kin domain-containing protein. | CMP/dCMP-type deaminase domain-containing protein. | 0.967 |
A0A0C3NI95 | A0A0C3PNN1 | A0A0C3NI95 | A0A0C3PNN1 | Thymidylate_kin domain-containing protein. | Uncharacterized protein. | 0.723 |
A0A0C3NI95 | A0A0C3PUF9 | A0A0C3NI95 | A0A0C3PUF9 | Thymidylate_kin domain-containing protein. | Pribosyltran domain-containing protein. | 0.429 |
A0A0C3NI95 | M404DRAFT_8727 | A0A0C3NI95 | A0A0C3P106 | Thymidylate_kin domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.647 |
A0A0C3P7M1 | A0A0C3PNN1 | A0A0C3P7M1 | A0A0C3PNN1 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Uncharacterized protein. | 0.760 |
A0A0C3P7M1 | M404DRAFT_8727 | A0A0C3P7M1 | A0A0C3P106 | Uncharacterized protein; Belongs to the DEAD box helicase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.560 |