node1 | node2 | node1 annotation | node2 annotation | score |
A0A4Z1K7M1 | A0A4Z1KA00 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | 0.636 |
A0A4Z1K7M1 | A0A4Z1KNL1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.876 |
A0A4Z1K7M1 | A0A4Z1KWS9 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.806 |
A0A4Z1K7M1 | A0A4Z1KZL4 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Uncharacterized protein. | 0.471 |
A0A4Z1K7M1 | A0A4Z1L048 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. | 0.506 |
A0A4Z1K7M1 | A0A4Z1L4T6 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GTP_cyclohydroI domain-containing protein. | 0.756 |
A0A4Z1KA00 | A0A4Z1K7M1 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.636 |
A0A4Z1KA00 | A0A4Z1KIF5 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.688 |
A0A4Z1KA00 | A0A4Z1KNL1 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.655 |
A0A4Z1KA00 | A0A4Z1KQ15 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.719 |
A0A4Z1KA00 | A0A4Z1KUV2 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.621 |
A0A4Z1KA00 | A0A4Z1KWS9 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.617 |
A0A4Z1KA00 | A0A4Z1KZL4 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Uncharacterized protein. | 0.714 |
A0A4Z1KA00 | A0A4Z1L048 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. | 0.764 |
A0A4Z1KA00 | A0A4Z1L164 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. | 0.629 |
A0A4Z1KA00 | A0A4Z1L4T6 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | GTP_cyclohydroI domain-containing protein. | 0.718 |
A0A4Z1KIF5 | A0A4Z1KA00 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | 0.688 |
A0A4Z1KIF5 | A0A4Z1KQ15 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.887 |
A0A4Z1KIF5 | A0A4Z1KZL4 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | Uncharacterized protein. | 0.967 |
A0A4Z1KIF5 | A0A4Z1L164 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. | 0.952 |