STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
shn_05840Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (279 aa)    
Predicted Functional Partners:
shn_06280
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
  
 
0.927
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 0.923
shn_00470
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 
0.900
shn_05825
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
shn_05830
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
shn_05835
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
shn_07125
DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.752
shn_05850
Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.715
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
     0.665
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.617
Your Current Organism:
Shinella sp. HZN7
NCBI taxonomy Id: 879274
Other names: S. sp. HZN7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.