STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
queGDomain of unknown function DUF1730; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (310 aa)    
Predicted Functional Partners:
queA-2
S-adenosylmethionine:tRNAribosyltransferase-isom erase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
  
 0.745
queA
S-adenosylmethionine:tRNAribosyltransferase-isom erase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
  
 0.703
ruvB
Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.695
AEL26407.1
HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR006402:IPR006439:IPR005834; KEGG: lby:Lbys_1526 had-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Glycoprotease family protein/hydrolase, beta-phosphoglucomutase family; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1.
      0.581
AEL23901.1
methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
      0.504
AEL25851.1
ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
       0.481
AEL25852.1
Zinc/iron permease; PFAM: ZIP Zinc transporter; InterPro IPR003689; KEGG: mtt:Ftrac_2964 zinc/iron permease; PFAM: Zinc/iron permease; SPTR: Zinc/iron permease.
       0.462
AEL26793.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.421
AEL26792.1
PFAM: Homocysteine S-methyltransferase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase; COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: dfe:Dfer_2804 methionine synthase; PFAM: Homocysteine S-methyltransferase; SPTR: Methionine synthase.
 
   
 0.415
AEL28240.1
Pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: domain; Domain of unknown function; 4Fe-4S binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; [...]
     
 0.413
Your Current Organism:
Cyclobacterium marinum
NCBI taxonomy Id: 880070
Other names: C. marinum DSM 745, Cyclobacterium marinum DSM 745, Cyclobacterium marinum LMG 13164, Cyclobacterium marinum str. DSM 745, Cyclobacterium marinum strain DSM 745
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