STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB08032.1DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: mem:Memar_2179 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain; IMG reference gene:2504153655; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. (207 aa)    
Predicted Functional Partners:
AEB08371.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.976
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.972
AEB10399.1
PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterPro IPR004013:IPR002054:IPR003583:IPR003141; KEGG: geo:Geob_1150 PHP domain protein; PFAM: PHP, C-terminal; SMART: DNA-directed DNA polymerase X; Helix-hairpin-helix DNA-binding motif, class 1; Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP domain protein; IMG reference gene:2504156142; PFAM: PHP domain.
  
 0.932
AEB10000.1
COGs: COG0417 DNA polymerase elongation subunit (family B); InterPro IPR006172:IPR006134; KEGG: lbf:LBF_2104 DNA-directed DNA polymerase; PFAM: DNA-directed DNA polymerase, family B, conserved region; SMART: DNA-directed DNA polymerase, family B; SPTR: DNA polymerase B region; IMG reference gene:2504155725; PFAM: DNA polymerase family B.
   
 0.859
AEB08819.1
Histidinol-phosphate phosphatase family protein; COGs: COG0241 Histidinol phosphatase and related phosphatase; InterPro IPR005834:IPR006543:IPR006549; KEGG: aar:Acear_0221 hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Hydrolase, HAD-superfamily, subfamily IIIA; TIGRFAM: Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; IMG reference gene:2504154482; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosph [...]
   
 0.845
AEB10748.1
Metallophosphoesterase; InterPro IPR004843; KEGG: dma:DMR_35930 hypothetical protein; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; IMG reference gene:2504156521.
  
 0.786
AEB09477.1
COGs: COG0681 Signal peptidase I; InterPro IPR019759:IPR000223; KEGG: tye:THEYE_A0098 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; IMG reference gene:2504155173; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
    
 0.773
AEB08601.1
KEGG: xcv:XCV2168 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504154250.
   
 0.764
AEB09579.1
DNA repair ATPase; COGs: COG0419 ATPase involved in DNA repair; KEGG: sat:SYN_02754 DNA repair ATPase; SPTR: ATPases involved in DNA repair; IMG reference gene:2504155288.
   
 0.764
AEB09205.1
Helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR000330; KEGG: bts:Btus_2854 helicase domain protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: Helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: Helicase domain protein; IMG reference gene:2504154887; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
  
 0.760
Your Current Organism:
Desulfobacca acetoxidans
NCBI taxonomy Id: 880072
Other names: D. acetoxidans DSM 11109, Desulfobacca acetoxidans DSM 11109, Desulfobacca acetoxidans str. DSM 11109, Desulfobacca acetoxidans strain DSM 11109
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