STRINGSTRING
ltaE protein (Desulfovibrio vulgaris Hildenborough) - STRING interaction network
"ltaE" - Threonine aldolase, low-specificity in Desulfovibrio vulgaris Hildenborough
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ltaEThreonine aldolase, low-specificity; Identified by similarity to SP-O50584 (340 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism; Belongs to the SHMT family (412 aa)
     
  0.969
gcvPB
Glycine dehydrogenase (aminomethyl-transferring); Identified by similarity to SP-P54377; Belongs to the GcvP family (481 aa)
   
 
  0.923
thrC
Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260 (470 aa)
     
  0.915
DVU_3121
Aminotransferase, class V; Identified by match to protein family HMM PF00266 (376 aa)
   
 
  0.912
gcvPA
Probable glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. N-terminal subunit subfamily (443 aa)
       
  0.911
DVU_3294
Aldehyde dehydrogenase (NADP) family protein; Identified by match to protein family HMM PF00171 (464 aa)
         
  0.908
DVU_1879
Glycosyl transferase, group 1 family protein; Identified by match to protein family HMM PF00534 (366 aa)
   
        0.840
gcvT
Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM TIGR00528 (362 aa)
     
 
  0.553
DVU_0462
Chorismate mutase/prephenate dehydratase; Identified by similarity to SP-P07022; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807 (391 aa)
         
  0.540
DVU_2147
L-serine dehydratase, putative; Identified by match to protein family HMM PF03313; match to protein family HMM PF03315 (502 aa)
 
     
  0.411
Your Current Organism:
Desulfovibrio vulgaris Hildenborough
NCBI taxonomy Id: 882
Other names: D. vulgaris str. Hildenborough, Desulfovibrio vulgaris (STRAIN HILDENBOROUGH), Desulfovibrio vulgaris ATCC 29579, Desulfovibrio vulgaris Hildenborough, Desulfovibrio vulgaris str. Hildenborough, Desulfovibrio vulgaris subsp. vulgaris (strain Hildenborough), Desulfovibrio vulgaris subsp. vulgaris ATCC 29579, Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough
Server load: low (16%) [HD]