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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDHD1DDHD domain-containing protein. (237 aa)    
Predicted Functional Partners:
TXNDC16
Thioredoxin domain containing 16.
      
 0.849
STYX
Serine/threonine/tyrosine interacting protein.
   
  
 0.806
DDHD2
DDHD domain containing 2.
   
 
0.787
GPR137C
G protein-coupled receptor 137C.
      
 0.748
RTRAF
RNA transcription, translation and transport factor.
      
 0.748
PSMC6
Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.
   
  
 0.642
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.627
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.621
PTGER2
Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family.
     
 0.617
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
    
 
 0.613
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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