STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDE1NudE neurodevelopment protein 1. (342 aa)    
Predicted Functional Partners:
NDEL1
Uncharacterized protein.
  
0.997
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 0.996
NUDC
Nuclear distribution C, dynein complex regulator.
     
 0.965
PLK1
Serine/threonine-protein kinase PLK.
     
 0.960
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.957
DISC1
DISC1 scaffold protein.
    
 
 0.930
MAPRE1
Microtubule associated protein RP/EB family member 1.
    
 0.912
TSNARE1
t-SNARE domain containing 1.
    
   0.881
CENPF
Uncharacterized protein.
    
 0.862
ENSAPLP00000019716
CENP-F_N domain-containing protein.
    
 0.862
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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