STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDE1NudE neurodevelopment protein 1. (342 aa)    
Predicted Functional Partners:
NUDC
Nuclear distribution C, dynein complex regulator.
     
 0.932
PLK1
Serine/threonine-protein kinase PLK.
     
 0.894
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.893
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 
 0.857
DISC1
DISC1 scaffold protein.
    
 
 0.826
NDEL1
Uncharacterized protein.
  
 
 
0.727
TBC1D31
TBC1 domain family member 31.
    
 
 0.706
HAUS6
HAUS6_N domain-containing protein.
     
 0.665
MARF1
Meiosis regulator and mRNA stability factor 1.
      
 0.635
ASPM
Abnormal spindle microtubule assembly.
      
 0.611
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.