STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHHSonic hedgehog signaling molecule. (391 aa)    
Predicted Functional Partners:
PTCH1
Patched 1.
   
 0.997
HHIP
Hedgehog interacting protein.
    
 0.990
DISP1
Dispatched RND transporter family member 1.
   
 0.987
CDON
Cell adhesion associated, oncogene regulated.
    
 0.984
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.979
PTCH2
SSD domain-containing protein.
   
 0.977
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.939
GLI1
GLI family zinc finger 1.
   
 0.929
GLI2
Uncharacterized protein.
   
 0.923
LRP2
LDL receptor related protein 2.
     
 0.919
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.