STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF1Interferon regulatory factor 1. (439 aa)    
Predicted Functional Partners:
MDM2
Uncharacterized protein.
    
 0.928
STAT1
Signal transducer and activator of transcription.
   
 0.918
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
   
 
 0.806
SOCS1
Suppressor of cytokine signaling 1.
   
 0.793
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.784
USP18
USP domain-containing protein; Belongs to the peptidase C19 family.
   
 0.756
STAT3
Signal transducer and activator of transcription.
   
 0.756
IRF2
Interferon regulatory factor 2.
  
0.753
ENSAPLP00000024056
SH2 domain-containing protein.
   
 0.751
ENSAPLP00000027532
Link domain-containing protein.
   
 0.751
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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