STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFV41280.1Hypothetical protein. (168 aa)    
Predicted Functional Partners:
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.815
SFV41355.1
O-acetyltransferase.
  
     0.646
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.603
SFV40446.1
Serine/threonine protein kinase PrkC, regulator of stationary phase.
  
  
 0.506
SFV39960.1
PTS system, sucrose-specific IIB component / PTS system, sucrose-specific IIC component.
  
     0.488
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.460
parE
Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
   
 
 0.460
LAC1533_0180
Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
    
 
 0.457
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.445
SFV41113.1
DNA topoisomerase III.
  
 
 0.445
Your Current Organism:
Lactobacillus acidipiscis
NCBI taxonomy Id: 89059
Other names: CCUG 42961 [[Lactobacillus cypricasei]], CCUG 46556, CIP 106393 [[Lactobacillus cypricasei]], CIP 106750, DSM 15353 [[Lactobacillus cypricasei]], DSM 15836, JCM 10692, KCTC 13900 [[Lactobacillus cypricasei]], L. acidipiscis, Lactobacillus acidipiscis Tanasupawat et al. 2000, Lactobacillus cypricasei, Lactobacillus cypricasei Lawson et al. 2001, Lactobacillus sp. FS60-1, Lactobacillus sp. FS60-1T, Lactobacillus sp. LMG 17676, Lactobacillus sp. LMK3, NBRC 102163, NRIC 0300, PCU 207, PCU:207, strain FS60-1, strain LMK3 [[Lactobacillus cypricasei]]
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