STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
ISM_09296Putative two-component sensor histidine kinase protein; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system. (623 aa)    
Predicted Functional Partners:
ISM_09291
Hypothetical protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 0.985
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
0.982
ISM_13495
C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.
  
  
 
0.925
ISM_11185
C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 0.893
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
0.870
ISM_13500
C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 0.836
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
0.786
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
  
 0.772
ISM_12885
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
 0.711
ISM_01565
Response regulator receiver protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
  
 0.694
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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