Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_12445COG1564 Thiamine pyrophosphokinase. (205 aa)    
Predicted Functional Partners:
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.855
ISM_17360
TraF protein; COG0840 Methyl-accepting chemotaxis protein.
   
   0.608
ISM_12440
Lipoprotein, putative.
       0.607
ISM_10651
COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
    
 0.533
ISM_09005
COG0584 Glycerophosphoryl diester phosphodiesterase.
  
  
  0.517
ISM_00740
Hypothetical protein; COG3173 Predicted aminoglycoside phosphotransferase.
    
  0.440
ISM_10576
Hypothetical protein; COG0510 Predicted choline kinase involved in LPS biosynthesis.
     
  0.427
ISM_07765
Hypothetical protein; COG1653 ABC-type sugar transport system, periplasmic component.
     
  0.423
ISM_16085
Putative thiamine-phosphate pyrophosphorylase; COG0352 Thiamine monophosphate synthase.
     
 0.418
ISM_08725
S-formylglutathione hydrolase, putative; Serine hydrolase involved in the detoxification of formaldehyde.
   
    0.412
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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