STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFM22245.1Small GTP-binding protein domain protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: small GTP-binding protein domain. (636 aa)    
Predicted Functional Partners:
AFM22244.1
Fe2+ transport system protein A; PFAM: FeoA domain.
 
  
 0.993
AFM22243.1
Hypothetical protein.
       0.476
topA
DNA topoisomerase I, bacterial; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removi [...]
      
 0.422
Your Current Organism:
Acetomicrobium mobile
NCBI taxonomy Id: 891968
Other names: A. mobile DSM 13181, Acetomicrobium mobile ATCC BAA-54, Acetomicrobium mobile DSM 13181, Anaerobaculum mobile ATCC BAA-54, Anaerobaculum mobile DSM 13181, Anaerobaculum mobile NGA
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