STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRP1Uncharacterized protein. (1791 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.655
AGRN
Agrin.
    
 0.621
DKK1
Dickkopf WNT signaling pathway inhibitor 1.
    
 0.587
RELN
Reelin.
    
 0.567
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
    
 0.552
PCSK9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.534
DAB2
PID domain-containing protein.
    
 0.533
DAB1
PID domain-containing protein.
    
 0.509
KREMEN1
Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.
    
 0.482
A306_00010685
Ovoinhibitor.
    
 0.473
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.