STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A306_00014986Guanylate cyclase. (842 aa)    
Predicted Functional Partners:
GUCA1B
Guanylate cyclase activator 1B (Retina).
   
 0.939
GUCA1A
Guanylate cyclase activator 1A (Retina).
   
 0.935
A306_00014190
Guanylyl cyclase-activating protein 1.
   
 0.929
GUCA1C
Guanylate cyclase activator 1C.
    
 0.923
NUDT2
Nudix (Nucleoside diphosphate linked moiety X)-type motif 2, transcript variant X1.
     
 0.905
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
     
 0.905
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.905
GUCY2F
Guanylate cyclase.
  
  
 
0.901
A306_00006759
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.901
ITPA
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
    
  0.900
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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