STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STAT3Signal transducer and activator of transcription. (771 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.989
JAK1
Tyrosine-protein kinase.
   
 0.981
FOXO1
Forkhead box O1.
   
 0.928
FOXO3
Forkhead box O3.
   
 0.928
SOCS3
Suppressor of cytokine signaling 3.
   
 0.924
A306_00012651
Forkhead box protein O3-like.
   
 0.914
FOXO4
Forkhead box O4.
   
 0.914
EP300
E1A binding protein p300.
    
 0.897
A306_00004891
Histone acetyltransferase p300-like.
    
 0.897
IL6
Interleukin 6.
   
 0.889
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.