STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)    
Predicted Functional Partners:
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.961
A306_00007955
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.961
A306_00007954
Guanine nucleotide-binding protein subunit alpha-14.
    
 0.961
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
  
  
0.952
CASR
Calcium-sensing receptor.
     
 0.936
GNAI2
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2.
   
 0.931
GNAI1
Guanine nucleotide-binding protein G(I) subunit alpha-1.
   
 0.931
GPRC6A
G protein-coupled receptor, class C, group 6, member A.
     
 0.929
ITPR3
Inositol 1,4,5-trisphosphate receptor, type 3.
   
 0.921
ITPR1
Inositol 1,4,5-trisphosphate receptor, type 1.
   
 0.921
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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