STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DFFADNAation factor, 45kDa, alpha polypeptide. (303 aa)    
Predicted Functional Partners:
DFFB
DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase).
    
 0.987
CASP3
Caspase 3, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.983
CASP7
Caspase 7, apoptosis-related cysteine peptidase, transcript variant X1; Belongs to the peptidase C14A family.
    
 0.644
CENPU
Centromere protein U.
    
 0.644
CASP6
Caspase 6, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.626
CIDEC
Cell death-inducing DFFA-like effector c.
    
 
 0.570
CASP2
Caspase 2, apoptosis-related cysteine peptidase, transcript variant X1; Belongs to the peptidase C14A family.
    
 0.560
CASP9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.553
JAGN1
Jagunal homolog 1.
      
 0.521
APIP
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
      
 0.434
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.