Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BRAF | GRB2 | ENSGALP00000020950 | ENSGALP00000012993 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.649 |
| BRAF | MAP2K1 | ENSGALP00000020950 | ENSGALP00000050365 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.982 |
| BRAF | MAP2K2 | ENSGALP00000020950 | ENSGALP00000001932 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). | 0.983 |
| BRAF | MAPK3 | ENSGALP00000020950 | ENSGALP00000002278 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Mitogen-activated protein kinase. | 0.817 |
| BRAF | MOS | ENSGALP00000020950 | ENSGALP00000049891 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Serine/threonine-protein kinase mos; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. | 0.900 |
| BRAF | RAF1 | ENSGALP00000020950 | ENSGALP00000046736 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | RAF proto-oncogene serine/threonine-protein kinase; Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions. RAF1 activation initiates a mitogen- activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2) (By similarity). | 0.989 |
| GRB2 | BRAF | ENSGALP00000012993 | ENSGALP00000020950 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.649 |
| GRB2 | MAP2K1 | ENSGALP00000012993 | ENSGALP00000050365 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.661 |
| GRB2 | MAP2K2 | ENSGALP00000012993 | ENSGALP00000001932 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). | 0.680 |
| GRB2 | RAF1 | ENSGALP00000012993 | ENSGALP00000046736 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | RAF proto-oncogene serine/threonine-protein kinase; Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions. RAF1 activation initiates a mitogen- activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2) (By similarity). | 0.581 |
| LAMTOR3 | MAP2K1 | ENSGALP00000060460 | ENSGALP00000050365 | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.943 |
| LAMTOR3 | MAP2K2 | ENSGALP00000060460 | ENSGALP00000001932 | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). | 0.942 |
| LAMTOR3 | MAPK3 | ENSGALP00000060460 | ENSGALP00000002278 | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | Mitogen-activated protein kinase. | 0.917 |
| MAP2K1 | BRAF | ENSGALP00000050365 | ENSGALP00000020950 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.982 |
| MAP2K1 | GRB2 | ENSGALP00000050365 | ENSGALP00000012993 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.661 |
| MAP2K1 | LAMTOR3 | ENSGALP00000050365 | ENSGALP00000060460 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Ragulator complex protein LAMTOR3; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids. Adapter protein that may regulate the MAP kinase cascade (By similarity). | 0.943 |
| MAP2K1 | MAP2K2 | ENSGALP00000050365 | ENSGALP00000001932 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). | 0.939 |
| MAP2K1 | MAP3K1 | ENSGALP00000050365 | ENSGALP00000023686 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase kinase 1. | 0.953 |
| MAP2K1 | MAP3K4 | ENSGALP00000050365 | ENSGALP00000056606 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase kinase 4. | 0.693 |
| MAP2K1 | MAP3K8 | ENSGALP00000050365 | ENSGALP00000068369 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase kinase 8. | 0.931 |
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