node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CASP3 | LOC101747587 | ENSGALP00000068843 | ENSGALP00000053353 | Caspase-3; Belongs to the peptidase C14A family. | Polyubiquitin-B; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; L [...] | 0.529 |
CASP3 | MIB2 | ENSGALP00000068843 | ENSGALP00000002233 | Caspase-3; Belongs to the peptidase C14A family. | E3 ubiquitin-protein ligase MIB2; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. | 0.830 |
CASP3 | RIPK1 | ENSGALP00000068843 | ENSGALP00000036418 | Caspase-3; Belongs to the peptidase C14A family. | Uncharacterized protein. | 0.887 |
CASP3 | RPS27A | ENSGALP00000068843 | ENSGALP00000050085 | Caspase-3; Belongs to the peptidase C14A family. | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] | 0.516 |
CASP3 | TRADD | ENSGALP00000068843 | ENSGALP00000005055 | Caspase-3; Belongs to the peptidase C14A family. | TNFRSF1A associated via death domain. | 0.821 |
CASP3 | TRAF2 | ENSGALP00000068843 | ENSGALP00000070161 | Caspase-3; Belongs to the peptidase C14A family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.716 |
CASP3 | UBA52 | ENSGALP00000068843 | ENSGALP00000062168 | Caspase-3; Belongs to the peptidase C14A family. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.499 |
CYLD | LOC101747587 | ENSGALP00000016104 | ENSGALP00000053353 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | Polyubiquitin-B; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; L [...] | 0.801 |
CYLD | MIB2 | ENSGALP00000016104 | ENSGALP00000002233 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | E3 ubiquitin-protein ligase MIB2; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. | 0.851 |
CYLD | RIPK1 | ENSGALP00000016104 | ENSGALP00000036418 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | Uncharacterized protein. | 0.981 |
CYLD | RPS27A | ENSGALP00000016104 | ENSGALP00000050085 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] | 0.881 |
CYLD | TRADD | ENSGALP00000016104 | ENSGALP00000005055 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | TNFRSF1A associated via death domain. | 0.951 |
CYLD | TRAF2 | ENSGALP00000016104 | ENSGALP00000070161 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.764 |
CYLD | UBA52 | ENSGALP00000016104 | ENSGALP00000062168 | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.858 |
KIAA1524 | MIB2 | ENSGALP00000024744 | ENSGALP00000002233 | Protein CIP2A homolog. | E3 ubiquitin-protein ligase MIB2; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. | 0.761 |
LOC101747587 | CASP3 | ENSGALP00000053353 | ENSGALP00000068843 | Polyubiquitin-B; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; L [...] | Caspase-3; Belongs to the peptidase C14A family. | 0.529 |
LOC101747587 | CYLD | ENSGALP00000053353 | ENSGALP00000016104 | Polyubiquitin-B; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; L [...] | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. | 0.801 |
LOC101747587 | MIB2 | ENSGALP00000053353 | ENSGALP00000002233 | Polyubiquitin-B; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; L [...] | E3 ubiquitin-protein ligase MIB2; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. | 0.806 |
LOC101747587 | RIPK1 | ENSGALP00000053353 | ENSGALP00000036418 | Polyubiquitin-B; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; L [...] | Uncharacterized protein. | 0.610 |
LOC101747587 | RPS27A | ENSGALP00000053353 | ENSGALP00000050085 | Polyubiquitin-B; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; L [...] | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] | 0.996 |